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Moreover, we have also explored the involvement of GPXs in plant growth and developmental processes

Some researchers have proposed that concentrations above approximately 6 to 7 mol/L may already indicate suboptimal methylation and increased long term health risk

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In support of this is the fact that the concentrations of biomarkers of B 12 function, methylmalonic acid and homocysteine increase in the later stages of pregnancy (Reference Murphy, Molloy and Ueland57,Reference Milman, Byg and Bergholt58) suggesting some level of metabolic B 12 depletion in pregnant women