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In terms of immunology, hormones play a pivotal role by actively controlling the synthesis of antimicrobial peptides (such as -defensins) and cytokines that promote inflammation

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While exposure patterns vary, the following toxins are most commonly associated with chronic indoor mold illness: Ochratoxin A (OTA) Produced by species of Aspergillus and Penicillium , ochratoxin A has been associated with: Mitochondrial dysfunction Oxidative stress Renal strain Neurotoxicity (12,13) Aflatoxins Produced by Aspergillus flavus and Aspergillus parasiticus , aflatoxins are potent hepatotoxins and immunomodulators