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IGF 1 LR3 (Long R3 Insulin-like Growth Factor-I or Long R3IGF-I) is an 83 amino acid analog of human IGF-I actually comprising the complete human IGF 1 LR3 sequence but with the substitution of an Arg for the Glu at position 3, as well as a 13 amino acid extension peptide at the N-terminus

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18H04794), the Naito Foundation, a research grant from the Princess Takamatsu Cancer Research Fund 15-24728, the Uehara Memorial Foundation, and Japan Agency for Medical Research and Development (JP19gm5010002)