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demonstrated the presence and potential function of caspases in RBCs [22]

Abstract Glutathione is a tripeptide synthesized at cytosolic level, that exists in cells in a reduced form (thiol-reduced-GSH-) and in an oxidized form (disulfide-oxidized)

Concentrations of GSH, GSSG and the ratio between GSH and GSSG (GSH/GSSG), used as a proper value to evaluate the redox balance in these cells, are reported in Table 2

While purine nucleotide synthesis is selectively affected through Nrf2 activation, c-Myc is involved in the regulation of both purine and pyrimidine nucleotide synthesis

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