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Supporting this mechanism, studies in animal models demonstrate that L-carnitine administration increases the expression of mitochondrial superoxide dismutase-2 (SOD2), reduces markers of inflammation, and alleviates overall oxidative burden (63)

It may be that these types of cancer are less sensitive to IGF-1, or that other risk factors such as smoking are dominant, Dr Knppel comments

TABLE 1 Summary of key studies investigating ferroptosis in recurrent miscarriage and related disorders

doi: 10.1161/JAHA.117.008190 183 KangDWParkMKOhHJLeeDGParkSHChoiKYet al