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Realistic weight loss timelines Based on clinical trial data and real-world experience, here is what to expect at each phase of treatment: Month 1 (0.25-0.5 mg): 2-5 pounds of weight loss, primarily from reduced caloric intake and some water weight

Thats true for classically regulated drugs and medications, where the FDA has approved the drug, the manufacturing methods, and even the labeling on the bottle and the box

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Some foods like refined grains, refined fats, processed foods and sugar might deplete your niacin status, so balance those out with the foods highest in niacin: liver, fish, poultry, other meat, and peanut butter