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Lyophilization is a sophisticated process where the material is frozen and then the surrounding pressure is reduced to allow the frozen water to sublimate directly from a solid to a gas

Allergic Reactions: Rash, swelling, or breathing difficulties (very rare)

However, interpretation of these signatures may be confounded by kidney function and medication use, and clinical translation will require rigorous external validation, particularly in prospective cohorts and trials specifically designed for DKD

10.3390/ijms131113926 225 SchmidN.BtschiM.van GunsterenW

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