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Markunas and colleagues (Markunas et al., 2014) showed that DNA methylation is changed in 110 gene regions and notably FRMD4A , a gene associated with Alzheimer disease (AD) and nicotine dependence and CNTNAP2 , a gene associates with neural development, autism spectrum disorder, schizophrenia, and language impairment

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The short answer to all of these questions is that we do not know, but there is reason to be concerned, because we do know that smoking is associated with increased risk of depression, marijuana use, binge drinking, and use of other drugs including opioids

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Rohaizad added that three local lorry drivers, in their 40s and 50s, were detained to assist in the investigation