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Enjoy cleaner, smoother smoke while maintaining the taste youre used to

We excluded studies reporting only former exposure to SHS and those only assessing exposure in specific public settings

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A mixed factorial design was used

These materials are frequently discarded or incinerated, creating environmental disposal challenges due to their high nicotine content ( Microbial compatibility and detoxification A critical factor in utilizing tobacco-derived media for fermentation is the presence of alkaloids, particularly nicotine, which can inhibit microbial growth at elevated concentrations