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Ferroptosis is a type of cell death linked to altered iron metabolism, glutathione (GSH) depletion, GSH peroxidase 4 (GPX4) inactivation, and increased OxS, which is a prominent clinical feature of COVID-19 27,348

Drug-induced liver injury has been reported, so pretreatment evaluation should include checking levels of liver enzymes and bilirubin in addition to the usual laboratory testing performed before administration of biologicals

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All cell lines were regularly tested for Acholeplasma, Ureaplasma and Mycoplasma contamination as described [24]