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compared the efficacy of IA injections of PRP, HA, and a combination of both in hip OA

Available human studies are characterized by relatively small sample sizes, heterogeneity in dosing regimens, and short intervention durations, which restrict the ability to draw firm conclusions regarding efficacy and optimal therapeutic windows

Blood levels of triglycerides, urea and bilirubin were not significantly affected and indicated that the overall liver function remained efficient in both mice genotypes (data not shown)

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