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So, these are much safer B12 values: As Sally and Jeffrey note: At this time, we believe normal serum B12 levels should be greater than 550 pg/ml

The fluorescence signal was measured at the end of each extension step

This could in part be due to the lower levels of ApoE in the CNS of ApoE4 carriers (Flowers and Rebeck, 2020), thus offering less overall antimicrobial protection, but also mechanistically as ApoE4 prevents HSV-1 cellular attachment but crucially not viral entry or replication, and can also be incorporated into the HSV-1 virion that can enhance release from the cell (Feng et al., 2023), which would be an issue for viral AD

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Results were submitted in 2016 but never posted, and the submission cycle is marked as canceled