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The MYC-driven metabolic program highlights the indispensable role of glutamine as a key player in the continuous proliferation associated with several cancer types [30]

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In severe osteoarthritis, the limiting problem is often structural joint degeneration

Human and canine patients with IVD degeneration can thus be used as a study population to investigate the mechanisms of degeneration and potential regenerative treatments, which is beneficial for both species and suits the 'One Health concept

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