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If liver biopsy is performed, the hallmark histopathological feature is accumulation of coarse brown-black granules typically seen on hematoxylin and eosin staining, predominantly within the cytoplasm of centrilobular (zone 3) hepatocytes, sparing the periportal areas

The rationale is mechanistic extrapolation, not demonstrated synergy

An increase in appetite can be a hit or miss for most individuals

Nobody has systematically documented Dihexas side effects in humans, which is itself the biggest red flag

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