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In short, it appears that smoking is responsible for a good deal of the divergence in female life expectancy being examined here

Compared with case-control studies [39, 40], prospective studies may lose some statistical power, but estimates of the absolute risk support using the PRS to predict incident lung cancer [10, 41]

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Studies also suggest vaping may impair immune function and contribute to long-term neurological effects due to nicotines impact on brain development