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FDX1s dual role in energy metabolism and oxidative stress reduction positions it as a therapeutic target for age-related declines in oocyte competence, particularly in IVF settings where mitochondrial dysfunction is prevalent

Quercetin and ellagic acid demonstrate synergistic effects in p53 phosphorylation, stimulating BAX expression and translocation of p53 protein into mitochondria, ultimately resulting in pro-apoptotic effects

Cell grouping and treatment Cigarette smoke extract (CSE) was prepared by bubbling the smoke from two cigarettes into 20 mL of serum-free DMEM, which was then filtered with a 0.2 m filter to sterilize the mixture

Yang X, Chen Y, Song W, Huang T, Wang Y, Chen Z, et al

The DOH must provide additional clarity on the use of IV glutathione, particularly outside of hospital settings