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38,39 The current data revealed that ROF inhibited the activation of p53 induced by MTX

KPV exerts its anti-inflammatory function inside colonic cells, which inactivates inflammatory pathways by reducing pro-inflammatory cytokine genetic expression

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A previous clinical trial aimed at correcting the HHcy induced by metformin in PCOS patients found that metformin did indeed significantly increase circulating Hcy and that folic acid reduced it only by 8% compared to a 21% reduction with a multivitaminic approach (B1, B6, and B12) [24]

Paralelamente, el GHK-Cu aumenta la expresin de la lisil oxidasa, la enzima responsable de la reticulacin de las fibras de colgeno y elastina, reforzando as la arquitectura tridimensional de la matriz extracelular