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In a healthy individual, the body's antioxidant reservesled by glutathionequickly sweep in to neutralize these free radicals once the infection clears

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The NMNAT1 and NMNAT3 transgenic mouse strains used here were as previously described (Yahata et al, 2009), and the colony was maintained through breeding heterozygous males with wild-type females, with a subsequent Mendelian ratio of offspring to be used for experiments of 50% heterozygous transgenics, and 50% wild-type littermate controls

Short-Acting: Allows study of physiological pulsatile GH release