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And I wish it was as easy as saying You should use this much and calling it a day

Athough annotated plant GPXs use TRXs more efficiently than GSH, at least two other types of enzyme could be important in peroxidation of glutathione (Figure 6)

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Importantly, inefficient elimination of mitochondria in red blood cell (RBC) precursors of sickle-cell disease patients results in mitochondrial retention in mature erythrocytes with consequent increased ROS generation and accelerated hemolysis [60, 61]