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(2016, Indian Journal of Dermatology, Venereology and Leprology ) the most comprehensive published review on this topic concluded that the evidence for intravenous glutathione as a skin-lightening agent remains limited and of low quality

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The copper(II) complex adds one copper ion plus typically a coordinated water or hydroxide molecule, depending on conditions, giving the complex an overall mass in the range of approximately 400-420 daltons