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Nicotine Tob Res 26(9):11501158 Azzopardi D, Ebajemito J, McEwan M et al (2022a) A randomised study to assess the nicotine pharmacokinetics of an oral nicotine pouch and two nicotine replacement therapy products

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Nicotine addiction develops through repeated exposure to nicotine, which alters the brains chemistry and creates a cycle of dependence

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Hookahs use a heat source usually made from lit charcoal which produces significant amounts of toxic substances at the time of combustion