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C.de WeerthC.et al

Clinical trials showed that cholecalciferol (vitamin D) supplementation, especially in patients with TB having 1,25(OH)2D deficiency, may augment standard anti-TB therapy (ATT) by accelerating sputum culture conversion and improving lesion absorption [7, 76]

By tagging the substrates with ubiquitin, E3 ligases provide a platform for protein-protein interactions that can modulate the activity, localization or interaction of the target proteins, thereby triggering different biological signals to regulate a variety of cellular processes including cell cycle, cell division, stress response, DNA repair and apoptosis etc 1,2,3,4

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GSH, GSSG, markers of lipid peroxidation and DNA oxidation, and IL-8 were quantified in the BAL supernatant