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Physical damage: Punctures, crushing, or impact during handling or waste processing can compromise internal components and trigger thermal runaway

Cigarettes has nothing to do with Life, A Users Manual , but his having done the book did inspire me

So Selye began to suggest that subjecting an animal to prolonged stress led to tissue changes and physiological changes with the release of certain hormones, that would then cause disease and ultimately the death of the animal." And so the idea of stress and it's potential costs to the body was born

And forget harm