114 Ni II , like Zn II and Mn II , can perform Lewis acid chemistry, exemplified by two hydrolytic enzymes, the dinuclear Ni II enzyme urease (Section 5.1.2) and the mononuclear glyoxylase-I, but also functions as a cofactor in [NiFe]-hydrogenase and Ni-superoxide dismutase, among others, where both the Ni I and Ni III oxidation states must be accessible
D., et al., The Enzymes of the Oxidative Phase of the Pentose Phosphate Pathway as Targets of Reactive Species: Consequences for NADPH Production, Biochemical Society Transactions 51, no
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c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions
They are often referred to as membrane lipids, but animal and human studies have revealed roles for PCs in energy metabolism, lipoprotein transport and cell signaling (van der Veen et al