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All applications are confined to laboratory studies

Chronic reduction of dietary energy intake without malnutrition decreases adiposity, inflammation and improves metabolic profiles (3,4)

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These kinases phosphorylate the membrane transporters (DAT, NET, SERT), leading to two outcomes: the transporters are either internalized into the cell (ceasing all reuptake function) or they undergo a conformational shift that causes them to operate in reverse

While unique substances can be utilized to create functional and nutraceutical products with patentable rights, most products contain "free" ingredients that can be easily duplicated, giving the inventor company's competitive advantages lessened (Jalgaonkar et al., 2019)