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The activity of Mfn2 is also regulated by signal transducer molecule 2 (recombinant mothers against decapentaplegic homolog 2, Smad2), which acts as a scaffold to recruit Rab-Ras interacting factor 1 (RIN1) to form the Smad2-RIN1-Mfn2 complex with Mfn2, which ultimately promotes ATP synthesis and mitochondrial fusion (Kumar et al., 2016)

Graphical Abstract Similar content being viewed by others 1 Introduction Photosensitive compounds derived from porphyrins, chlorins, and phthalocyanines have been intensively investigated for photodynamic treatment (PDT) of cancer [1,2,3]

An ensemble of the ten lowest energy structural models is shown in Fig

10.1016/j.ejphar.2006.01.037 Eur