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This typically involves: Intrinsic factor antibodies (highly specific for pernicious anaemia, though sensitivity is only 50%) [12] [28] Gastric parietal cell antibodies (more sensitive but less specific) Coeliac serology if malabsorption is suspected Consideration of upper gastrointestinal endoscopy in selected cases, particularly with autoimmune gastritis/pernicious anaemia NICE guidance emphasises that treatment should not be delayed whilst awaiting antibody results if clinical features strongly suggest deficiency, as irreversible neurological damage can occur

Historiallinen tausta ja tieteellinen konteksti Tieteellinen Kiinnostus synteettisi peptidikomplekseja kohtaan on kasvanut merkittvsti molekyylibiologian ja biokemiallisen tutkimuksen kehittyess

T gel =1.8 (% F127)+1.3 (% F68)+53 An equation is fitted to the data obtained and can be utilized to estimate the Mean Dissolution Time (hr) based on the gelation temperature of F127/F68 mixtures (for 17-25% F127 and 0-10% F68), using results obtained in examples above: MDT= 0.2 ( T gel )+8