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MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types
Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells
Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2
FLT3 and c-Kit
Olaparib (AZD2281
Z-VAD-FMK Pack Size:1 mg MMAE is widely used asZ VAD FMK (Z VAD(OH) FMK) is a well know pan caspase inhibitor, which does not inhibit ubiquitin carboxy terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 M.
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