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Nobody can give you an honest probability of harm because the studies that would generate one have not been done

If you're unsure how long an opened vial has been at room temperature, refrigerate it immediately and mentally note the date you first opened it

For a confirmed deficiency, their guidelines point to a specific type of B12 called hydroxocobalamin, given as an intramuscular injection

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Some people take B12 injections short-term to correct a deficiency, while others use them long-term for ongoing support, especially if they have: We recommend getting lab tests periodically to assess B12 levels and determine if continued supplementation is necessary