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These actions contribute to improved cognitive function, reduced disease progression, and enhanced brain health

In addition, TMP exhibits anti-inflammatory effects by inhibiting pro-inflammatory pathways, such as NF-B and p38 MAPK, thereby reducing the expression of inflammatory markers, including cyclooxygenase-2 and TNF-

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Interestingly, some metabolites such as malate, -ketoglutarate, ornithine, glutamate, ornithine, phenylalanine, tryptophan, tyrosine, leucine, and histidine had higher percentage 13 C-labelling in three or more carbon atoms (M+ 3) in the gdh3 / gdh3 mutant compared to wild-type cells grown in 30% U- 13 C 5 proline medium

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