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Cells of passage between P3 and P10 were used for all experiments, and cells for the same experiment originated from the same number of passages

Further confirmation of fumarate as an oncometabolite was verified by experimental data showing that tumor cells lost their ability to invade and migrate when the function of fumarate hydratase was restored by an external expression vector 131

Tani H, Dulla CG, Farzampour Z, Taylor-Weiner A, Huguenard JR, Reimer RJ

WO2019167070A1 - Topical copper tripeptide composition and process of preparation

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